Quantity not sufficient rates and delays in sweat testing in US infants with cystic fibrosis

Background Diagnostic sweat testing is required for infants with positive newborn‐screening (NBS) tests for cystic fibrosis (CF). Infants have “quantity not sufficient” (QNS) sweat volumes more often than older children. A comprehensive study of QNS sweat volumes in infants has not previously been r...

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Veröffentlicht in:Pediatric pulmonology 2020-11, Vol.55 (11), p.3053-3056
Hauptverfasser: McColley, Susanna A., Elbert, Alexander, Wu, Runyu, Ren, Clement L., Sontag, Marci K., LeGrys, Vicky A.
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Sprache:eng
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Zusammenfassung:Background Diagnostic sweat testing is required for infants with positive newborn‐screening (NBS) tests for cystic fibrosis (CF). Infants have “quantity not sufficient” (QNS) sweat volumes more often than older children. A comprehensive study of QNS sweat volumes in infants has not previously been reported. Methods We surveyed US CF Centers to obtain QNS rates in all infants who had sweat testing at under 14 days and under 3 months of age. We then calculated QNS rates reported to the Cystic Fibrosis Foundation Patient Registry (CFFPR) 2010‐2018 in 10‐day increments from 1 to 60 days of life. We compared QNS sweat test rates in preterm (
ISSN:8755-6863
1099-0496
DOI:10.1002/ppul.25027