The birth of artemisinin

As the first-line antimalarial drugs, artemisinins gained wide acceptance after the emergence of resistance to chloroquine in the 1950s. Artemisinin-based drugs have saved lives, especially in developing countries. The discovery of artemisinin was unique, timely, and fascinating, and the benefits of...

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Veröffentlicht in:Pharmacology & therapeutics (Oxford) 2020-12, Vol.216, p.107658-107658, Article 107658
Hauptverfasser: Ma, Nan, Zhang, Ziyue, Liao, Fulong, Jiang, Tingliang, Tu, Youyou
Format: Artikel
Sprache:eng
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Zusammenfassung:As the first-line antimalarial drugs, artemisinins gained wide acceptance after the emergence of resistance to chloroquine in the 1950s. Artemisinin-based drugs have saved lives, especially in developing countries. The discovery of artemisinin was unique, timely, and fascinating, and the benefits of artemisinin were with far-reaching implications. Herein, we will give a brief description of various aspects of the development of artemisinin and discuss the position and perspectives of artemisinin-based drugs.
ISSN:0163-7258
1879-016X
DOI:10.1016/j.pharmthera.2020.107658