Clinical significance of advanced lung cancer inflammation index, a nutritional and inflammation index, in gastric cancer patients after surgical resection: A propensity score matching analysis

The advanced lung cancer inflammation index (ALI) has recently been shown as a prognostic marker for several cancers. However, its predictive value for surgical and oncological outcomes in gastric cancer (GC) remains unclear. We retrospectively reviewed the preoperative ALI in 620 GC patients receiv...

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Veröffentlicht in:Clinical nutrition (Edinburgh, Scotland) Scotland), 2021-03, Vol.40 (3), p.1130-1136
Hauptverfasser: Yin, Chengzeng, Toiyama, Yuji, Okugawa, Yoshinaga, Omura, Yusuke, Kusunoki, Yukina, Kusunoki, Kurando, Imaoka, Yuki, Yasuda, Hiromi, Ohi, Masaki, Kusunoki, Masato
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Sprache:eng
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Zusammenfassung:The advanced lung cancer inflammation index (ALI) has recently been shown as a prognostic marker for several cancers. However, its predictive value for surgical and oncological outcomes in gastric cancer (GC) remains unclear. We retrospectively reviewed the preoperative ALI in 620 GC patients receiving gastrectomy to elucidate the prognostic value for overall survival (OS) and disease-free survival (DFS) and to clarify its predictive value for perioperative risk of surgical site infection (SSI) in GC patients. Propensity score matching (PSM) analysis was also conducted to certify these potentials of preoperative ALI. Preoperative low ALI was significantly correlated with advanced tumor–node–metastasis stage classification. Patients with low ALI showed poorer OS (p 
ISSN:0261-5614
1532-1983
DOI:10.1016/j.clnu.2020.07.018