Senna (Cassia) alata (Linn.) Roxb. leaf decoction as a treatment for tinea imbricata in an indigenous tribe in Southern Philippines

Background Tinea imbricata, a rare form of tinea corporis caused by Trichophyton concentricum, is endemic to the T’boli tribe in the Southern Philippines. Temporary remissions and limited access to antifungal medications make its treatment a pressing public health concern. Anecdotal reports about th...

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Veröffentlicht in:Mycoses 2020-11, Vol.63 (11), p.1226-1234
Hauptverfasser: Eusebio‐Alpapara, Kathleen May V., Dofitas, Belen L., Balita‐Crisostomo, Cherry Lou A., Tioleco‐Ver, Giselle Marie S., Jandoc, Lilibeth E., Frez, Ma. Lorna F.
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Sprache:eng
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Zusammenfassung:Background Tinea imbricata, a rare form of tinea corporis caused by Trichophyton concentricum, is endemic to the T’boli tribe in the Southern Philippines. Temporary remissions and limited access to antifungal medications make its treatment a pressing public health concern. Anecdotal reports about the use of Senna alata leaf decoction as treatment exist. Objective To determine the efficacy of community‐prepared S alata leaf decoction in the treatment of tinea imbricata. Methods Tinea imbricata patients were instructed to apply S alata leaf decoction for 4 weeks (28 ± 3 days). Disease severity, pruritus visual analogue scale scores (VAS) and potassium hydroxide (KOH) mounts of skin scrapings were evaluated before and after treatment. Two assessors evaluated disease severity based on photographs. Cohen's kappa statistics were used to assess diagnostic concordance. Adverse drug events were recorded. Results Twenty patients were enrolled. After 4 weeks, 95% had decreased pruritus VAS scores, with a mean decreased of 4.05 after treatment (P 
ISSN:0933-7407
1439-0507
DOI:10.1111/myc.13159