Treatment of Chronic Lymphocytic Leukemia

Treatment of Chronic Lymphocytic Leukemia

Treatment of CLL, the most common leukemia in the West, has undergone a revolution in the past few years with the development of agents that target signaling kinases and cell-survival mediators. Survival even among patients with a poor prognosis now exceeds 8 years.

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Bibliographische Detailangaben
Veröffentlicht in:The New England journal of medicine 2020-07, Vol.383 (5), p.460-473
1. Verfasser: Burger, Jan A
Format: Artikel
Sprache:eng
Schlagworte:
Anemia
Antigens
Bone marrow
Cell survival
Chemotherapy
Chronic lymphocytic leukemia
Cloning
Genes
Immunoglobulins
Kinases
Leukemia
Life expectancy
Lymphatic leukemia
Lymphatic system
Lymphoma
Medical prognosis
Mutation
Pathogenesis
Spleen
Thrombocytopenia
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Beschreibung
Zusammenfassung:Treatment of CLL, the most common leukemia in the West, has undergone a revolution in the past few years with the development of agents that target signaling kinases and cell-survival mediators. Survival even among patients with a poor prognosis now exceeds 8 years.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMra1908213