Relation of microvascular dysfunction and exercise tolerance in patients with heart failure with preserved ejection fraction

Relation of microvascular dysfunction and exercise tolerance in patients with heart failure with preserved ejection fraction

Purpose We aimed to investigate the association of coronary flow reserve (CFR) with exercise tolerance (ET) in subjects with heart failure with preserved ejection fraction (HFpEF). Materials and Methods Seventy‐seven patients with HFpEF were recruited for the study and compared with 30 healthy match...

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Veröffentlicht in:Echocardiography (Mount Kisco, N.Y.) N.Y.), 2020-08, Vol.37 (8), p.1192-1198
Hauptverfasser: Mahfouz, Ragab A., Gouda, Mohammad, Abdelhamid, Mohamed
Format: Artikel
Sprache:eng
Schlagworte:
coronary flow
exercise intolerance
heart failure
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Zusammenfassung:Purpose We aimed to investigate the association of coronary flow reserve (CFR) with exercise tolerance (ET) in subjects with heart failure with preserved ejection fraction (HFpEF). Materials and Methods Seventy‐seven patients with HFpEF were recruited for the study and compared with 30 healthy matched age and sex controls. All subjects underwent comprehensive echocardiographic evaluation. Exercise tolerance was assessed using 6‐minute walking test (6 MWT). CFR was calculated with adenosine stress transthoracic Doppler echocardiography. Results Out of 77 patients with HFpEF, 51 (66%) had CFR 
ISSN:0742-2822
1540-8175
DOI:10.1111/echo.14799