Critical analysis of lymph node examination in patients undergoing curative‐intent resection for adrenocortical carcinoma

Background Adrenocortical carcinoma (ACC) is a rare tumor and the role of lymph node dissection remains ill‐defined. This study evaluates the effect of nodal examination on prognosis and survival in patients undergoing curative‐intent resection of ACC. Methods The National Cancer Database (2004‐2015...

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Veröffentlicht in:Journal of surgical oncology 2020-11, Vol.122 (6), p.1152-1162
Hauptverfasser: Deschner, Benjamin W., Stiles, Zachary E., DeLozier, Olivia M., Drake, Justin A., Tsao, Miriam, Glazer, Evan S., Deneve, Jeremiah L., Yakoub, Danny, Dickson, Paxton V.
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Sprache:eng
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Zusammenfassung:Background Adrenocortical carcinoma (ACC) is a rare tumor and the role of lymph node dissection remains ill‐defined. This study evaluates the effect of nodal examination on prognosis and survival in patients undergoing curative‐intent resection of ACC. Methods The National Cancer Database (2004‐2015) was queried for patients undergoing margin‐negative resection for ACC. Patients with distant metastases, neoadjuvant therapy, multivisceral resection and T4 tumors were excluded. Results Among 897 patients, 147 (16.4%) had lymph nodes examined. Factors associated with lymph node examination included increasing tumor size (P 
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.26138