Neuroprotective Effect Of Peptide Fractions from Chia (Salvia hispanica) on H2O2-Induced Oxidative Stress-Mediated Neuronal Damage on N1E-115 Cell Line

Neuroprotective Effect Of Peptide Fractions from Chia (Salvia hispanica) on H2O2-Induced Oxidative Stress-Mediated Neuronal Damage on N1E-115 Cell Line

Neurodegenerative diseases (ND) affect around a billion people worldwide. Oxidative stress plays a critical role in the activation of neuronal death mechanisms, implicated in the ND etiology. In the present research, the neuroprotective effect of the S. hispanica protein derivatives is evaluated, on...

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Veröffentlicht in:Neurochemical research 2020-10, Vol.45 (10), p.2278-2285
Hauptverfasser: Martínez Leo, Edwin E., Segura Campos, Maira R.
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Biomedical and Life Sciences
Biomedicine
Cell Biology
Neurochemistry
Neurology
Neurosciences
Original Paper
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Zusammenfassung:Neurodegenerative diseases (ND) affect around a billion people worldwide. Oxidative stress plays a critical role in the activation of neuronal death mechanisms, implicated in the ND etiology. In the present research, the neuroprotective effect of the S. hispanica protein derivatives is evaluated, on neuronal cells N1E-115, after the damage induction with H 2 O 2 . From the protein-rich fraction of S. hispanica, three peptide fractions were obtained (3–5, 1–3 y
ISSN:0364-3190
1573-6903
DOI:10.1007/s11064-020-03085-0