Prevalence of Depression or Depressive Symptoms in Patients with Narcolepsy: a Systematic Review and Meta-Analysis

Prevalence of Depression or Depressive Symptoms in Patients with Narcolepsy: a Systematic Review and Meta-Analysis

A meta-analysis was conducted to review the prevalence and associated moderators of depression or depressive symptoms in patients with narcolepsy. An extensive search of the literature yielded 1104 articles and abstracts, of which 31 studies were included in the meta-analysis. Meta-analysis revealed...

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Veröffentlicht in:Neuropsychology review 2021-03, Vol.31 (1), p.89-102
Hauptverfasser: Li, Xiao, Sanford, Larry D., Zong, Qiang, Zhang, Ye, Tan, Lu, Li, Taomei, Ren, Rong, Zhou, Junying, Han, Fang, Tang, Xiangdong
Format: Artikel
Sprache:eng
Schlagworte:
Biomedical and Life Sciences
Biomedicine
Confidence intervals
Mental depression
Meta-analysis
Narcolepsy
Neurology
Neuropsychology
Neurosciences
Review
Sleep disorders
Systematic review
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Zusammenfassung:A meta-analysis was conducted to review the prevalence and associated moderators of depression or depressive symptoms in patients with narcolepsy. An extensive search of the literature yielded 1104 articles and abstracts, of which 31 studies were included in the meta-analysis. Meta-analysis revealed that the overall pooled prevalence of depression or depressive symptoms in patients with narcolepsy was 32% (95% Confidence Interval, 28–36%) with high between-study heterogeneity ( Q  = 249.77, df = 30, p  
ISSN:1040-7308
1573-6660
DOI:10.1007/s11065-020-09443-7