Hypertrophic Cardiomyopathy ― A Heterogeneous and Lifelong Disease in the Real World

Hypertrophic cardiomyopathy (HCM) is the most frequent hereditary cardiomyopathy, showing an autosomal-dominant f inheritance. A great deal of attention has been paid to genetics, left ventricular tract obstruction and the prediction and prevention of sudden cardiac death in HCM. Needless to say, th...

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Veröffentlicht in:Circulation Journal 2020/07/22, Vol.84(8), pp.1218-1226
Hauptverfasser: Kitaoka, Hiroaki, Kubo, Toru, Doi, Yoshinori L.
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Sprache:eng
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Zusammenfassung:Hypertrophic cardiomyopathy (HCM) is the most frequent hereditary cardiomyopathy, showing an autosomal-dominant f inheritance. A great deal of attention has been paid to genetics, left ventricular tract obstruction and the prediction and prevention of sudden cardiac death in HCM. Needless to say, these are very important, but we should recognize the heterogeneity in etiology, morphology, clinical course and management of this unique cardiomyopathy. Another important perspective is that HCM causes left ventricular remodeling over time and is a disease that requires lifelong management in the real world.
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-20-0524