Caveolae Spelunking: Exploring a New Modality in Tensional Homeostasis

Caveolae Spelunking: Exploring a New Modality in Tensional Homeostasis

In this issue of Developmental Cell, Teo et al. (2020) uncover how caveolae control a PIP -FMNL2 pathway that regulates tensional homeostasis at cell-cell junctions. They further examine caveolae-mediated tensional dysregulation and its functional consequences in oncogenic cell extrusion.

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Bibliographische Detailangaben
Veröffentlicht in:Developmental cell 2020-07, Vol.54 (1), p.3-5
Hauptverfasser: Cavanaugh, Kate E, Chmiel, Theresa A, Gardel, Margaret L
Format: Artikel
Sprache:eng
Schlagworte:
Caveolae
Epithelium
Homeostasis
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Beschreibung
Zusammenfassung:In this issue of Developmental Cell, Teo et al. (2020) uncover how caveolae control a PIP -FMNL2 pathway that regulates tensional homeostasis at cell-cell junctions. They further examine caveolae-mediated tensional dysregulation and its functional consequences in oncogenic cell extrusion.
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2020.06.016