Release and targeting of polycystin-2-carrying ciliary extracellular vesicles

Release and targeting of polycystin-2-carrying ciliary extracellular vesicles

Wang et al. examine sensory-evoked ciliary extracellular vesicle (EV) release and targeting in C. elegans. They find that males deposit PKD-2-carrying EVs onto the vulva of the hermaphrodite during mating and that mechanical stimulation triggers release of these PKD-2-carrying vesicles from cilia.

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Veröffentlicht in:Current biology 2020-07, Vol.30 (13), p.R755-R756
Hauptverfasser: Wang, Juan, Nikonorova, Inna A., Gu, Amanda, Sternberg, Paul W., Barr, Maureen M.
Format: Artikel
Sprache:eng
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Zusammenfassung:Wang et al. examine sensory-evoked ciliary extracellular vesicle (EV) release and targeting in C. elegans. They find that males deposit PKD-2-carrying EVs onto the vulva of the hermaphrodite during mating and that mechanical stimulation triggers release of these PKD-2-carrying vesicles from cilia.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2020.05.079