Intramolecularly stapled amphipathic peptides via a boron-sugar interaction
Amadori products (deoxyfructosyllysine derivatives) that can selectively interact with phenylboronic acids and borate ions were synthesized. The intramolecular interactions between the fructosyl moiety and phenylboronic acid incorporated into various positions of the peptide chain were investigated...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2020-08, Vol.56 (62), p.8814-8817 |
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| container_title | Chemical communications (Cambridge, England) |
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| creator | Kijewska, Monika Czerwińska, Angelika Al-Harthi, Samah Wołczański, Grzegorz Waliczek, Mateusz Emwas, Abdul-Hamid Jaremko, Mariusz Jaremko, Łukasz Stefanowicz, Piotr Szewczuk, Zbigniew |
| description | Amadori products (deoxyfructosyllysine derivatives) that can selectively interact with phenylboronic acids and borate ions were synthesized. The intramolecular interactions between the fructosyl moiety and phenylboronic acid incorporated into various positions of the peptide chain were investigated using high-resolution mass spectrometry (HR-MS), circular dichroism (CD), and nuclear magnetic resonance (NMR). |
| doi_str_mv | 10.1039/d0cc02603d |
| format | Article |
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| ispartof | Chemical communications (Cambridge, England), 2020-08, Vol.56 (62), p.8814-8817 |
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| language | eng |
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| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Boron Boron - chemistry Chemical synthesis Dichroism Hydrophobic and Hydrophilic Interactions Mass spectrometry Models, Molecular NMR Nuclear magnetic resonance Peptides Peptides - chemistry Protein Conformation Sugars - chemistry |
| title | Intramolecularly stapled amphipathic peptides via a boron-sugar interaction |
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