Idiopathic non-necrotizing eosinophilic vasculitis limited to the lung: Part of a complex spectrum

The hallmark of this proposed new entity is the concomitant presence of blood and tissue eosinophilia together with histologic and clinical features of necrotizing vasculitis. [...]our patient had lung nodules, alveolar hemorrhage, and abundant pleural effusion, which are uncommon in EGPA.3 Moreover...

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Veröffentlicht in:The journal of allergy and clinical immunology in practice (Cambridge, MA) MA), 2020-07, Vol.8 (7), p.2454-2455
Hauptverfasser: Nasser, Mouhamad, Thivolet-Béjui, Françoise, Cottin, Vincent
Format: Artikel
Sprache:eng
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Zusammenfassung:The hallmark of this proposed new entity is the concomitant presence of blood and tissue eosinophilia together with histologic and clinical features of necrotizing vasculitis. [...]our patient had lung nodules, alveolar hemorrhage, and abundant pleural effusion, which are uncommon in EGPA.3 Moreover, histopathologic features corresponded to non-necrotizing EoV1 and differed from EGPA even lung-limited.2 Differentiating EoV from EGPA may be challenging, however, because the 3 histologic cardinal features of EGPA may not be found in the same tissue sample,4 and ANCAs are only found in
ISSN:2213-2198
2213-2201
DOI:10.1016/j.jaip.2020.04.027