Influence of border-age on survival of sporadic renal cell carcinoma: young adults versus octogenarians

Purpose To compare the effects of two border-age groups: young adults and octogenarians on survival of sporadic renal cell carcinoma (RCC). Methods We reviewed the records of 1619 patients that underwent radical or partial nephrectomy due to RCC between January 2004 and December 2018 in two high-volume centers. Patients were divided into two groups based on their age: ≤ 40 years old (group 1) and ≥ 80 years old (group 2). We analyzed the demographic, clinical and histological features of the groups and performed univariable and multivariable Cox regression analyses to evaluate predictors associated with survival. Results Median ages of patients were 35.5 years and 82 years in group 1 ( n = 90) and group 2 ( n = 55), respectively. Radical nephrectomy rate was statistically higher in group 2 ( p = 0.004). Median follow-up was 72 (11–192) months in group 1 and 30 months (5–103) in group 2 ( p