Systemic Immune-Inflammation Index Predicts Overall Survival in Patients with Gastric Cancer: a Propensity Score–Matched Analysis

Systemic Immune-Inflammation Index Predicts Overall Survival in Patients with Gastric Cancer: a Propensity Score–Matched Analysis

Background The systemic immune-inflammation index (SII), integrated by peripheral lymphocyte, neutrophil, and platelet counts, is used as an objective biomarker that reflects the balance between host inflammatory and immune response status in cancer patients. Herein, we examined the prognostic signi...

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Veröffentlicht in:Journal of gastrointestinal surgery 2021-05, Vol.25 (5), p.1124-1133
Hauptverfasser: Hirahara, Noriyuki, Tajima, Yoshitsugu, Matsubara, Takeshi, Fujii, Yusuke, Kaji, Shunsuke, Kawabata, Yasunari, Hyakudomi, Ryoji, Yamamoto, Tetsu, Uchida, Yuki, Taniura, Takahito
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Gastric cancer
Gastroenterology
Humans
Inflammation
Medical prognosis
Medicine
Medicine & Public Health
Middle Aged
Multivariate analysis
Older people
Original Article
Prognosis
Propensity Score
Retrospective Studies
Stomach Neoplasms - surgery
Surgery
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Zusammenfassung:Background The systemic immune-inflammation index (SII), integrated by peripheral lymphocyte, neutrophil, and platelet counts, is used as an objective biomarker that reflects the balance between host inflammatory and immune response status in cancer patients. Herein, we examined the prognostic significance of SII in gastric cancer patients. Methods We retrospectively reviewed data of 415 patients who underwent curative laparoscopic gastrectomy using propensity score–matched (PSM) analysis. The prognostic value of SII was compared between two groups based on SII values: low SII group (SII 
ISSN:1091-255X
1873-4626
DOI:10.1007/s11605-020-04710-7