Risk factors associated with avascular fibrous membrane in patients with retinopathy of prematurity

Purpose We sought to assess the risk factors associated with avascular fibrous membrane development in patients with retinopathy of prematurity (ROP). Methods This retrospective, cross-sectional study included premature infants diagnosed with ROP. Gestational age, birth weight, stage and zone of the ROP, the presence of plus disease, and laser photocoagulation (LP) application were noted for each patient. Location, extension, development time, vanishing time of the avascular fibrous membrane, and associated complications were also noted. Patients who developed avascular fibrous membrane formed the membrane group ( n = 38) and those who did not develop avascular fibrous membrane formed the control group ( n = 208). Results Mean gestational age and birth weight did not differ between the groups ( p = 0.897 and p = 0.343). ROP developed significantly earlier in the control group than in the membrane group ( p