A Thermal Exhaust Port on the Death Star of Plasmodium falciparum-Infected Erythrocytes

Eliciting reliable and effective immunity against Plasmodium falciparum parasites remains an elusive goal in malaria control. Raj and colleagues recently described a naturally occurring human antibody response to a parasite antigen that initiates apoptosis-like cell death of parasites, adding fascin...

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Veröffentlicht in:Trends in pharmacological sciences (Regular ed.) 2020-08, Vol.41 (8), p.508-511
Hauptverfasser: Petersen, Jens E.V., Taylor, Steve M.
Format: Artikel
Sprache:eng
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Zusammenfassung:Eliciting reliable and effective immunity against Plasmodium falciparum parasites remains an elusive goal in malaria control. Raj and colleagues recently described a naturally occurring human antibody response to a parasite antigen that initiates apoptosis-like cell death of parasites, adding fascinating insight into host–pathogen dialog that may furnish actionable targets for antiparasite therapies or vaccines.
ISSN:0165-6147
1873-3735
DOI:10.1016/j.tips.2020.06.005