Risk Factors for the 90-Day Prognosis Of Severe Heat Stroke: a Case-Control Study

BACKGROUND:Severe heat stroke is a clinical syndrome caused by host stress dysfunction due to heat stress and subsequent life-threatening organ dysfunction. We aimed to explore the early risk factors affecting the 90-day prognosis of severe heat stroke patients. METHODS:A case-control study was used to retrospectively analyze the clinical data of 117 severe heat stroke patients admitted to the ICU of the General Hospital of Southern Theater Command from April 2014 to May 2019. The risk factors affecting the 90-day mortality of the patients were analyzed, and subgroup analysis was performed comparing the complete recovery and the sequelae subgroups of survivors. RESULTS:Thirteen patients (11.1%) died within 90 days. The multivariate Cox risk regression model showed that cooling time (HR 4.87; 95% CI1.94-12.18; P = 0.001), heart rate (HR 1.04; 95% CI1.01–1.09; P = 0.027), and Sequential Organ Failure (SOFA) score (HR 1.41; 95% CI1.21–1.65; P