Genetics and pediatric hospital admissions, 1985 to 2017

Genetics and pediatric hospital admissions, 1985 to 2017

Purpose To determine the prevalence and sociodemographic and hospitalization history of genetic conditions in a sample of inpatients in a pediatric hospital in 2017, and to compare results with unpublished studies from 1985, 1995, and 2007. Methods Two weeks of admissions were classified according t...

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Veröffentlicht in:Genetics in medicine 2020-11, Vol.22 (11), p.1777-1785
Hauptverfasser: Gjorgioski, Stephanie, Halliday, Jane, Riley, Merilyn, Amor, David J., Delatycki, Martin B., Bankier, Agnes
Format: Artikel
Sprache:eng
Schlagworte:
Biomedical and Life Sciences
Biomedicine
Child
Hospitalization
Hospitals, Pediatric
Human Genetics
Humans
Laboratory Medicine
Length of Stay
Pediatrics
Prevalence
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Zusammenfassung:Purpose To determine the prevalence and sociodemographic and hospitalization history of genetic conditions in a sample of inpatients in a pediatric hospital in 2017, and to compare results with unpublished studies from 1985, 1995, and 2007. Methods Two weeks of admissions were classified according to a pre-existing categorization, based on genetic etiology, encompassing chromosomal and monogenic conditions, multifactorial (MF) conditions, and no known genetic cause. Results In 2017, 299 (16%) patients had chromosomal or monogenic conditions, 6–7% more than 2007 and 1995, but similar to 1985. Autosomal dominant (AD) conditions increased from
ISSN:1098-3600
1530-0366
DOI:10.1038/s41436-020-0871-9