Medium‐grade proteinuria is a risk factor for incident markers of chronic kidney disease

Medium‐grade proteinuria is a risk factor for incident markers of chronic kidney disease

Objective Medium‐grade proteinuria (100–500 mg/g creatinine) is common among people living with HIV/AIDS (PLWHA) but is often undetected or ignored. This prospective, observational cohort study examined medium‐grade proteinuria as a risk factor for markers of chronic kidney disease (CKD). Methods Qu...

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Veröffentlicht in:HIV medicine 2020-09, Vol.21 (8), p.481-491
Hauptverfasser: Schrader, SY, Zeder, AJ, Hilge, R, Bogner, JR, Seybold, U
Format: Artikel
Sprache:eng
Schlagworte:
chronic
Creatinine
early diagnosis
Glomerular filtration rate
HIV
Human immunodeficiency virus
kidney
Kidney diseases
Kidneys
Markers
Multivariate analysis
Phosphaturia
Proteinuria
renal insufficiency
Risk analysis
Risk factors
Tenofovir
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Zusammenfassung:Objective Medium‐grade proteinuria (100–500 mg/g creatinine) is common among people living with HIV/AIDS (PLWHA) but is often undetected or ignored. This prospective, observational cohort study examined medium‐grade proteinuria as a risk factor for markers of chronic kidney disease (CKD). Methods Quantitative urine samples were collected from 241 PLWHA without known renal disease at baseline between January 2009 and February 2011 and at follow‐up 240 weeks later. Multivariate analysis was performed to assess medium‐grade proteinuria as a risk factor for incident markers of CKD (estimated glomerular filtration rate
ISSN:1464-2662
1468-1293
DOI:10.1111/hiv.12881