CHA2DS2-VASc score as predictor of stroke and all-cause death in stable ischaemic heart disease patients without atrial fibrillation
Background Cerebrovascular and coronary artery disease share risk factors. The aim was to study CHA 2 DS 2 -VASc score as predictor of stroke incidence and death in a sample of patients with sinus rhythm and stable ischemic heart disease (sIHD) during long-term follow-up. Methods 1184 patients with...
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Veröffentlicht in: | Journal of neurology 2020-10, Vol.267 (10), p.3061-3068 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Background
Cerebrovascular and coronary artery disease share risk factors. The aim was to study CHA
2
DS
2
-VASc score as predictor of stroke incidence and death in a sample of patients with sinus rhythm and stable ischemic heart disease (sIHD) during long-term follow-up.
Methods
1184 patients with sIHD and without atrial fibrillation were included in this single-centre prospective cohort study between February 2000 and January 2004. Stroke and death prediction abilities of CHA
2
DS
2
-VASc score in this population were investigated.
Results
The median age was 66 (interquartile range (IQR), 60–73 years). The mean follow-up was 11.2 ± 10 years (maximum 17 years). Along this period, 137 patients (11.6% of the sample) suffered a stroke. The mean value of CHA
2
DS
2
-VASc score was 3.04 ± 1.36, with CHA
2
DS
2
-VASc score ≤ 4 in 85.5% of the sample. Higher CHA
2
DS
2
-VASc score at baseline was associated with higher risk of suffering stroke (Hazard Ratio = 1.36, 95% CI 1.20–1.54,
p
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ISSN: | 0340-5354 1432-1459 |
DOI: | 10.1007/s00415-020-09961-7 |