CHA2DS2-VASc score as predictor of stroke and all-cause death in stable ischaemic heart disease patients without atrial fibrillation

Background Cerebrovascular and coronary artery disease share risk factors. The aim was to study CHA 2 DS 2 -VASc score as predictor of stroke incidence and death in a sample of patients with sinus rhythm and stable ischemic heart disease (sIHD) during long-term follow-up. Methods 1184 patients with...

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Veröffentlicht in:Journal of neurology 2020-10, Vol.267 (10), p.3061-3068
Hauptverfasser: Sanchez Fernandez, Jose J., Ortiz, Martín Ruiz, Ballesteros, Francisca Montoro, Luque, Cristina Ogayar, Penas, Elías Romo, Ortega, Mónica Delgado, Rubio, Dolores Mesa
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Sprache:eng
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Zusammenfassung:Background Cerebrovascular and coronary artery disease share risk factors. The aim was to study CHA 2 DS 2 -VASc score as predictor of stroke incidence and death in a sample of patients with sinus rhythm and stable ischemic heart disease (sIHD) during long-term follow-up. Methods 1184 patients with sIHD and without atrial fibrillation were included in this single-centre prospective cohort study between February 2000 and January 2004. Stroke and death prediction abilities of CHA 2 DS 2 -VASc score in this population were investigated. Results The median age was 66 (interquartile range (IQR), 60–73 years). The mean follow-up was 11.2 ± 10 years (maximum 17 years). Along this period, 137 patients (11.6% of the sample) suffered a stroke. The mean value of CHA 2 DS 2 -VASc score was 3.04 ± 1.36, with CHA 2 DS 2 -VASc score ≤ 4 in 85.5% of the sample. Higher CHA 2 DS 2 -VASc score at baseline was associated with higher risk of suffering stroke (Hazard Ratio = 1.36, 95% CI 1.20–1.54, p  
ISSN:0340-5354
1432-1459
DOI:10.1007/s00415-020-09961-7