Severe cases of seasonal influenza and detection of seasonal A(H1N2) in Russia in 2018–2019

Severe cases of seasonal influenza and detection of seasonal A(H1N2) in Russia in 2018–2019

Data obtained from monitoring cases of severe influenza, cases of vaccinated individuals, and unique cases were used to describe influenza viruses that circulated in Russia in the 2018–2019 epidemic season. A high proportion of the mutations D222G/N in A(H1N1)pdm09 HA was detected in fatal cases. Vi...

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Veröffentlicht in:Archives of virology 2020-09, Vol.165 (9), p.2045-2051
Hauptverfasser: Kolosova, Natalia P., Ilyicheva, Tatyana N., Danilenko, Alexey V., Svyatchenko, Svetlana V., Goncharova, Natalia I., Bulanovich, Julia A., Torzhkova, Polina Yu, Durymanov, Alexander G., Gudymo, Andrei S., Shvalov, Alexander N., Susloparov, Ivan M., Tregubchak, Tatyana V., Gavrilova, Elena V., Maksyutov, Rinat A., Ryzhikov, Alexander B.
Format: Artikel
Sprache:eng
Schlagworte:
Biomedical and Life Sciences
Biomedicine
Brief Report
Infectious Diseases
Influenza
Influenza A
Medical Microbiology
NS1 protein
Virology
Viruses
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Zusammenfassung:Data obtained from monitoring cases of severe influenza, cases of vaccinated individuals, and unique cases were used to describe influenza viruses that circulated in Russia in the 2018–2019 epidemic season. A high proportion of the mutations D222G/N in A(H1N1)pdm09 HA was detected in fatal cases. Viruses of the B/Victoria lineage with deletions in HA were detected in Russia, and a reassortant seasonal influenza A(H1N2) virus was identified. A C-terminal truncation in the NS1 protein was detected in a substantial proportion of A(H3N2) viruses.
ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-020-04699-z