IgE sensitivity to Malassezia pachydermatis and mite allergens in dogs with atopic dermatitis

In this study, dogs with atopic dermatitis were separated into non-food-induced atopic dermatitis (NFIAD) group (n = 15) and food-induced atopic dermatitis (FIAD) group (n = 37) based on an elimination diet test. IgE reactivity for crude Malassezia pachydermatis (M. pachydermatis) and house dust mit...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2020-08, Vol.226, p.110070-110070, Article 110070
Hauptverfasser:	Ishimaru, Hironobu, Okamoto, Noriaki, Fujimura, Masato, Miyaji, Kazuki, Shimakura, Hidekatsu, Takase, Yukari, Mizukami, Keijiro, Uchiyama, Jumpei, DeBoer, Douglas J., Sakaguchi, Masahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology Allergens - pharmacology Animals canine atopic dermatitis Cell Extracts - pharmacology co-sensitization Dermatitis, Atopic - immunology Dermatitis, Atopic - veterinary Dog Diseases - immunology Dog Diseases - microbiology Dogs Food Hypersensitivity - veterinary Fungal Proteins - immunology house dust mite Immunoglobulin E - blood Immunoglobulin E - immunology Intradermal Tests - veterinary Malassezia - immunology Malassezia pachydermatis microbiome Mites - immunology
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Zusammenfassung:	In this study, dogs with atopic dermatitis were separated into non-food-induced atopic dermatitis (NFIAD) group (n = 15) and food-induced atopic dermatitis (FIAD) group (n = 37) based on an elimination diet test. IgE reactivity for crude Malassezia pachydermatis (M. pachydermatis) and house dust mites (HDM) allergen extracts was investigated in the two groups using fluorometric enzyme-linked immunosorbent assay (ELISA) and intradermal skin test (IDST). Nine (60%) of the 15 dogs in NFIAD group and 6 (16%) of the 37 dogs in FIAD group showed specific IgE for M. pachydermatis (Mann-Whitney U-test, P
ISSN:	0165-2427 1873-2534
DOI:	10.1016/j.vetimm.2020.110070