A highly sensitive poly-arginine based MIP as an electrochemical sensor for selective detection of dimetridazole

In this experiment, a highly effective electrochemical sensor based on a molecularly imprinted polymer has been developed for ultrasensitive detection of dimetridazole. The sensor was made by incorporating of dimetridazole as a template molecule during the electropolymerization of poly-arginine on a glassy carbon electrode. The modified electrode GCE/P-Arg@MIP was characterized by voltammetric and microscopic techniques. Differential pulse voltammetry method was used to detect target analyte under the optimum condition. The DPV response to dimetridazole was linear at 0.1 × 10−9 to 10 × 10−6 mol L−1 (R2 = 0.996), with a method detection limit (S/N = 3) of 0.1 × 10−9 mol L−1. Moreover, the proposed sensor shows satisfactory recovery ranges for the determination dimetridazole in commercially available egg, milk and honey samples. [Display omitted] •Highly effective electrochemical MIP sensor developed for ultrasensitive detection of dimetridazole.•GCE/P-Arg@MIP electrode was fabricated via electrochemical deposition technique.•The proposed sensor exhibited a wide linear detection range with an LOD of 0.1 nM.•The GCE/P-Arg@MIP sensor was applied to detect analyte in egg, milk and honey.