Management of atypical chronic lymphocytic leukemia presenting with extreme leukocytosis

Management of atypical chronic lymphocytic leukemia presenting with extreme leukocytosis

Atypical chronic lymphocytic lymphoma (CLL) with CCND1 translocation is poorly described, particularly in the era of modern inhibitors of the B-cell receptor pathway. We present a patient with atypical CLL who had a significant response to ibrutinib, highlighting the effectiveness of this agent in h...

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Veröffentlicht in:Clinical case reports 2020, Vol.8 (5), p.877-882
Hauptverfasser: Muddasani, Ramya, Talwar, Neel, Suarez-Londono, Jaime Andres, Braunstein, Marc
Format: Report
Sprache:eng
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Zusammenfassung:Atypical chronic lymphocytic lymphoma (CLL) with CCND1 translocation is poorly described, particularly in the era of modern inhibitors of the B-cell receptor pathway. We present a patient with atypical CLL who had a significant response to ibrutinib, highlighting the effectiveness of this agent in higher risk CLL subgroups.
ISSN:2050-0904
2050-0904
DOI:10.1002/ccr3.2773