Performance of screening MRI in high risk patients at initial versus subsequent screen

To compare the characteristics, outcomes, and performance metrics in women undergoing initial breast MRI screening versus subsequent screening. A retrospective database search identified screening MRIs performed at an academic practice from 2013 to 2015. MRIs were divided into two groups: (1) initial screens and (2) subsequent screens (interpreted with at least one prior MRI for comparison). Benignity was confirmed with pathology or >1-year follow-up. Malignancy was confirmed by pathology. Performance metrics were calculated. Comparisons were made using Binomial and Fisher's exact tests. We observed a higher rate of abnormal interpretations (52% vs. 19%; p