Clinical and anatomopathological features of eosinophilic oesophagitis in children and adults

Eosinophilic oesophagitis (EoE) is a chronic clinical-pathological disorder with an immunological basis characterised by symptoms of oesophageal dysfunction and, histologically, eosinophilic inflammation. To evaluate the clinical characteristics and differences in children and adults diagnosed with...

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Veröffentlicht in:Allergologia et immunopathologia 2020-11, Vol.48 (6), p.560-567
Hauptverfasser: Agulló-García, A., Cubero, J.L., Lezaun, A., Boné, J., Guallar, I., Colás, C.
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Sprache:eng
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Zusammenfassung:Eosinophilic oesophagitis (EoE) is a chronic clinical-pathological disorder with an immunological basis characterised by symptoms of oesophageal dysfunction and, histologically, eosinophilic inflammation. To evaluate the clinical characteristics and differences in children and adults diagnosed with EoE in a tertiary level hospital. Descriptive, retrospective and cross-sectional study. We randomly selected 40 children and 40 adults diagnosed with EoE between 2009 and 2016. The patient characteristics were analysed by means of epidemiological, clinical, diagnostic and therapeutic variables. The average age at diagnosis was 10 years (children) and 34 years (adults), with a higher frequency in males. The majority were sensitised to aeroallergens (77.5% children vs. 82.5% adults) and foods (75% children vs. 82.5% adults). Statistically significant differences were detected in sensitisation to fruits (p=0.007) and grains (p
ISSN:0301-0546
1578-1267
DOI:10.1016/j.aller.2020.03.009