Short and mid-term outcomes of multimodal treatment for locally-advanced non-small cell lung cancer in elderly patients

Short and mid-term outcomes of multimodal treatment for locally-advanced non-small cell lung cancer in elderly patients

Objective Multimodality treatments are effective for locally advanced non-small cell lung cancer (LA-NSCLC) showing benefits in overall (OS) and disease-free survival (DFS), but these options are frequently denied to elderly patients. Methods The objectives of this retrospective study were: to inves...

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Veröffentlicht in:General thoracic and cardiovascular surgery 2020-11, Vol.68 (11), p.1290-1297
Hauptverfasser: Bongiolatti, Stefano, Mazzoni, Francesca, Gonfiotti, Alessandro, Di Pierro, Giulia, Salvicchi, Alberto, Borgianni, Sara, Ferrari, Katia, Voltolini, Luca
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Cancer therapies
Carcinoma, Non-Small-Cell Lung - mortality
Carcinoma, Non-Small-Cell Lung - secondary
Carcinoma, Non-Small-Cell Lung - therapy
Cardiac Surgery
Cardiology
Cardiovascular disease
Chemotherapy
Chronic obstructive pulmonary disease
Combined Modality Therapy
Comorbidity
Disease-Free Survival
Female
Geriatrics
Health Services for the Aged
Humans
Italy
Length of stay
Lung cancer
Lung Neoplasms - mortality
Lung Neoplasms - pathology
Lung Neoplasms - therapy
Male
Medical personnel
Medicine
Medicine & Public Health
Morbidity
Mortality
Neoplasm Metastasis
Oncology
Original Article
Patients
Pneumonectomy
Population
Radiation therapy
Retrospective Studies
Statistical analysis
Surgical Oncology
Thoracic Surgery
Toxicity
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Zusammenfassung:Objective Multimodality treatments are effective for locally advanced non-small cell lung cancer (LA-NSCLC) showing benefits in overall (OS) and disease-free survival (DFS), but these options are frequently denied to elderly patients. Methods The objectives of this retrospective study were: to investigate mortality, morbidity and oncological outcomes of pulmonary resection after induction therapy (IT) for NSCLC in elderly patients. We divided the cohort into two: patients 
ISSN:1863-6705
1863-6713
DOI:10.1007/s11748-020-01384-5