Apolipoprotein B/A-I Ratio Predicts Lesion Severity and Clinical Outcomes in Diabetic Patients With Acute Coronary Syndrome

Background:Dyslipidemia plays a crucial role in acute coronary syndrome (ACS). Paucity of data is available concerning the effect of apolipoprotein (apo) B/A-I ratio on the severity and outcomes in diabetic patients with ACS. This study investigated these associations in a Chinese cohort undergoing...

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Veröffentlicht in:	Circulation Journal 2020/06/25, Vol.84(7), pp.1132-1139
Hauptverfasser:	Liu, Yue, Jia, Si-da, Yuan, De-shan, Xu, Na, Jiang, Lin, Gao, Zhan, Chen, Jue, Yang, Yue-jin, Gao, Run-lin, Xu, Bo, Yuan, Jin-qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute coronary syndrome Acute Coronary Syndrome - diagnostic imaging Acute Coronary Syndrome - mortality Acute Coronary Syndrome - therapy Aged Apolipoprotein Apolipoprotein A-I - blood Apolipoprotein B-100 - blood Biomarkers - blood China Diabetes Mellitus - diagnosis Diabetes Mellitus - mortality Dyslipidemias - blood Dyslipidemias - diagnosis Dyslipidemias - mortality Female Heart Disease Risk Factors Humans Male Middle Aged Myocardial Infarction - diagnostic imaging Myocardial Infarction - therapy Patient Admission Percutaneous Coronary Intervention - adverse effects Percutaneous Coronary Intervention - mortality Prospective Studies Recurrence Recurrent myocardial infarction Risk Assessment Severity of Illness Index Time Factors Treatment Outcome
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Zusammenfassung:	Background:Dyslipidemia plays a crucial role in acute coronary syndrome (ACS). Paucity of data is available concerning the effect of apolipoprotein (apo) B/A-I ratio on the severity and outcomes in diabetic patients with ACS. This study investigated these associations in a Chinese cohort undergoing percutaneous coronary intervention.Methods and Results:In 2013, a total of 2,563 diabetic patients concomitant with ACS were included. Patients were divided into 2 groups based on the apoB/apoA-I ratio on admission:
ISSN:	1346-9843 1347-4820 1347-4820
DOI:	10.1253/circj.CJ-19-1097