Promising Immuno-Oncology Options for the Future: Cellular Therapies and Personalized Cancer Vaccines

A common pathway for an effective immune anticancer response involves recognition of tumor neoantigens and subsequent targeting of cancer cells by T cells. In this article, we provide an overview of the current status of two approaches to directly enhance this interaction using either adoptive cell...

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Veröffentlicht in:American Society of Clinical Oncology educational book 2020-05, Vol.40 (40), p.1-e258
Hauptverfasser: Solomon, Benjamin J, Beavis, Paul A, Darcy, Philip K
Format: Artikel
Sprache:eng
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Zusammenfassung:A common pathway for an effective immune anticancer response involves recognition of tumor neoantigens and subsequent targeting of cancer cells by T cells. In this article, we provide an overview of the current status of two approaches to directly enhance this interaction using either adoptive cell therapy or personalized cancer vaccines with focus on recent advances in solid tumors, including lung cancer.
ISSN:1548-8748
1548-8756
DOI:10.1200/EDBK_281101