Heart Retransplantation for Coronary Allograft Vasculopathy in Children: 25 Years of Single-Center Experience

Heart Retransplantation for Coronary Allograft Vasculopathy in Children: 25 Years of Single-Center Experience

Pediatric end-stage heart disease is surgically managed by heart transplantation. A major complication of primary transplantation (PTx) is coronary allograft vasculopathy (CAV), a form of accelerated atherosclerosis. Retransplantation (RTx) has been the management of CAV; however, there is limited c...

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Veröffentlicht in:Transplantation proceedings 2020-06, Vol.52 (5), p.1394-1396
Hauptverfasser: Azeka, Estela, Walker, Thomas, Siqueira, Adailson Wagner da Silva, Penha, Juliano, Miana, Leonardo, Caneo, Luiz Fernando, Massoti, Maria Raquel, Tanamati, Carla, Miura, Nana, Jatene, Marcelo Biscegli
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Sprache:eng
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Zusammenfassung:Pediatric end-stage heart disease is surgically managed by heart transplantation. A major complication of primary transplantation (PTx) is coronary allograft vasculopathy (CAV), a form of accelerated atherosclerosis. Retransplantation (RTx) has been the management of CAV; however, there is limited comprehensive literature on this subject. Here we report 25 years of single-center experience in managing CAV with RTx and place it in the context of recent studies. A retrospective cohort study was undertaken on patients who underwent PTx 
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2020.03.012