Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis
Regenerative medicines that promote remyelination in multiple sclerosis (MS) are making the transition from laboratory to clinical trials. While animal models provide the experimental flexibility to analyze mechanisms of remyelination, here we discuss the challenges in understanding where and how re...
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| Veröffentlicht in: | Cell stem cell 2020-05, Vol.26 (5), p.617-619 |
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| container_title | Cell stem cell |
| container_volume | 26 |
| creator | Neumann, Bjoern Foerster, Sarah Zhao, Chao Bodini, Benedetta Reich, Daniel S. Bergles, Dwight E. Káradóttir, Ragnhildur Thóra Lubetzki, Catherine Lairson, Luke L. Zalc, Bernard Stankoff, Bruno Franklin, Robin J.M. |
| description | Regenerative medicines that promote remyelination in multiple sclerosis (MS) are making the transition from laboratory to clinical trials. While animal models provide the experimental flexibility to analyze mechanisms of remyelination, here we discuss the challenges in understanding where and how remyelination occurs in MS. |
| doi_str_mv | 10.1016/j.stem.2020.03.017 |
| format | Article |
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While animal models provide the experimental flexibility to analyze mechanisms of remyelination, here we discuss the challenges in understanding where and how remyelination occurs in MS.</description><identifier>ISSN: 1934-5909</identifier><identifier>EISSN: 1875-9777</identifier><identifier>DOI: 10.1016/j.stem.2020.03.017</identifier><identifier>PMID: 32386552</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Models, Animal ; Multiple Sclerosis - drug therapy ; Myelin Sheath ; Oligodendroglia ; Regenerative Medicine ; Remyelination</subject><ispartof>Cell stem cell, 2020-05, Vol.26 (5), p.617-619</ispartof><rights>2020 Elsevier Inc.</rights><rights>Copyright © 2020 Elsevier Inc. 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| ispartof | Cell stem cell, 2020-05, Vol.26 (5), p.617-619 |
| issn | 1934-5909 1875-9777 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete; Cell Press Free Archives; EZB Electronic Journals Library |
| subjects | Animals Models, Animal Multiple Sclerosis - drug therapy Myelin Sheath Oligodendroglia Regenerative Medicine Remyelination |
| title | Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis |
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