Finding a unifying SLE expression signature in a sea of heterogeneity

Finding a unifying SLE expression signature in a sea of heterogeneity

The heterogeneity of systemic lupus erythematosus (SLE) confounds the diagnosis and treatment of this disease, and attempts at disease stratification are nascent. Researchers have identified a common set of biomarkers in patients with SLE that could identify new therapeutic targets and lead to new c...

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Veröffentlicht in:Nature reviews. Rheumatology 2020-07, Vol.16 (7), p.357-358
Hauptverfasser: Wakeland, Edward, Raj, Prithvi
Format: Artikel
Sprache:eng
Schlagworte:
692/4023/1670/1613
692/53
Humans
Lupus
Lupus Erythematosus, Systemic - genetics
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
News & Views
news-and-views
Rheumatology
Systemic lupus erythematosus
Therapeutic applications
Therapeutic targets
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Beschreibung
Zusammenfassung:The heterogeneity of systemic lupus erythematosus (SLE) confounds the diagnosis and treatment of this disease, and attempts at disease stratification are nascent. Researchers have identified a common set of biomarkers in patients with SLE that could identify new therapeutic targets and lead to new clinical assays to help address this issue.
ISSN:1759-4790
1759-4804
DOI:10.1038/s41584-020-0422-4