Factors affecting the diagnostic performance of circumpapillary retinal nerve fibre layer measurement in glaucoma

Factors affecting the diagnostic performance of circumpapillary retinal nerve fibre layer measurement in glaucoma

Background/aimsTo identify factors that influence the diagnostic performance of circumpapillary retinal nerve fibre layer (RNFL) thickness measurements in the detection of primary open-angle glaucoma (POAG).Methods1592 eyes from 1076 healthy controls and 758 eyes from 502 patients with POAG underwen...

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Veröffentlicht in:British journal of ophthalmology 2021-03, Vol.105 (3), p.397-402
Hauptverfasser: Wong, Damon, Chua, Jacqueline, Baskaran, Mani, Tan, Bingyao, Yao, Xinwen, Chan, Samuel, Tham, Yih Chung, Chong, Rachel, Aung, Tin, Lamoureux, Ecosse Luc, Vithana, Eranga N, Cheng, Ching Yu, Schmetterer, Leopold
Format: Artikel
Sprache:eng
Schlagworte:
Age
Glaucoma
Medical diagnosis
Myopia
Population
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Zusammenfassung:Background/aimsTo identify factors that influence the diagnostic performance of circumpapillary retinal nerve fibre layer (RNFL) thickness measurements in the detection of primary open-angle glaucoma (POAG).Methods1592 eyes from 1076 healthy controls and 758 eyes from 502 patients with POAG underwent optical coherence tomography (OCT) imaging to assess RNFL parameters. Visual field (VF) mean deviation (MD) from standard automated perimetry was used to indicate severity in subjects with glaucoma.ResultsRNFL thickness significantly decreased with age (ρ=−0.10 to −0.16, p
ISSN:0007-1161
1468-2079
DOI:10.1136/bjophthalmol-2020-315985