Escherichiacoli–Specific CD4+ T Cells Have Public T-Cell Receptors and Low Interleukin 10 Production in Crohn’s Disease

Crohn’s disease (CD) likely represents decreased immune tolerance to intestinal bacterial antigens. Most CD patients have high titers of antibodies to intestinal commensal proteins, including the outer membrane porin C (OmpC) of Escherichia coli. By using major histocompatibility complex II tetramer...

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Veröffentlicht in:	Cellular and molecular gastroenterology and hepatology 2020, Vol.10 (3), p.507-526
Hauptverfasser:	Uchida, Amiko M., Boden, Elisa K., James, Eddie A., Shows, Donna M., Konecny, Andrew J., Lord, James D.
Format:	Artikel
Sprache:	eng
Schlagworte:	IL10 OmpC Public TCR Tetramer-Guided Epitope Mapping
Online-Zugang:	Volltext
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