Evaluation of LDL receptor and Scavenger Receptor, Class B, Type 1 in the malignant and benign breast tumors: The correlation with the expression of miR-199a-5p, miR-199b-5p and miR-455-5p

•Receptor expressions and lipoproteins were higher in the breast cancer.•The expression of miR-199b-5p was downregulated in the malignant tumors.•Expression of miR-199a/b-5p and miR-455-5p were correlated with Her2 status.•A positive correlation was observed between SR-B1 or LDLR with HDL-C or LDL-C.•The expression of miR-199b-5p was reversely associated with LDLR in the tumors. The purpose of present study was to examine the correlations of LDL (LDLR) and HDL (SR-B1) receptors with lipoproteins, miR-199a-5p, miR-199b-5p, miR-455-5p in the malignant and benign breast tumors. Total cholesterol-rich-lipoproteins and the receptors were determined using enzymatic-homogeneous and ELISA methods. The expression levels of miRNAs were detected by qRT-PCR. Receptor expressions and lipoproteins concentration were significantly higher in the malignant tumors (p