MOG-antibody-associated hypertrophic pachymeningitis

BACKGROUNDThe clinical spectrum of myelin oligodendrocyte glycoprotein (MOG)-antibody-associated disease is expanding.OBJECTIVETo describe an unusual case of MOG-antibody-associated hypertrophic pachymeningitis (HP).METHODSCase study.RESULTSA 57-year-old female presented with a generalised seizure o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Multiple sclerosis and related disorders 2020, Vol.42, p.102074-102074
Hauptverfasser:	Papathanasiou, Athanasios, Yeo, Jing-Ming, Humberstone, Miles, Hosseini, Akram A
Format:	Report
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	BACKGROUNDThe clinical spectrum of myelin oligodendrocyte glycoprotein (MOG)-antibody-associated disease is expanding.OBJECTIVETo describe an unusual case of MOG-antibody-associated hypertrophic pachymeningitis (HP).METHODSCase study.RESULTSA 57-year-old female presented with a generalised seizure on a background of 3 months history of progressive cognitive decline and behavioural changes. Brain Magnetic Resonance Imaging (MRI) revealed widespread pachymeningeal enhancement and hyperintense signal in both hippocampi. Cerebrospinal Fluid (CSF) examination was normal. The patient was found positive for MOG-antibody. She clinically improved with steroids and the MRI abnormalities completely resolved.CONCLUSIONSClinicians might consider testing for MOG-antibody in cases with HP.
ISSN:	2211-0356
DOI:	10.1016/j.msard.2020.102074