The prognostic value of the prognostic nutritional index and inflammation-based markers in obstructive colorectal cancer

The prognostic value of the prognostic nutritional index and inflammation-based markers in obstructive colorectal cancer

Purpose Inflammation-based markers predict long-term outcomes of various malignancies. We investigated the relationship between these markers and the long-term survival in obstructive colorectal cancer (OCRC) patients with self-expandable metallic colonic stents (SEMSs) who subsequently received cur...

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Veröffentlicht in:Surgery today (Tokyo, Japan) Japan), 2020-10, Vol.50 (10), p.1272-1281
Hauptverfasser: Sato, Ryuichiro, Oikawa, Masaya, Kakita, Tetsuya, Okada, Takaho, Abe, Tomoya, Yazawa, Takashi, Tsuchiya, Haruyuki, Akazawa, Naoya, Sato, Masaki, Ohira, Tetsuya, Harada, Yoshihiro, Okano, Haruka, Ito, Kei, Tsuchiya, Takashi
Format: Artikel
Sprache:eng
Schlagworte:
Medicine
Medicine & Public Health
Original Article
Surgery
Surgical Oncology
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Zusammenfassung:Purpose Inflammation-based markers predict long-term outcomes of various malignancies. We investigated the relationship between these markers and the long-term survival in obstructive colorectal cancer (OCRC) patients with self-expandable metallic colonic stents (SEMSs) who subsequently received curative surgery. Methods We retrospectively analyzed 72 consecutive pathological stage II and III OCRC patients between 2013 and 2019. The prognostic significance of the prognostic nutritional index (PNI), neutrophil–lymphocyte ratio (NLR), lymphocyte–monocyte ratio (LMR), and platelet–lymphocyte ratio (PLR) was evaluated. Results The overall survival (OS), cancer-specific survival, and disease-free survival (DFS) were significantly shorter in the PNI 
ISSN:0941-1291
1436-2813
DOI:10.1007/s00595-020-02007-5