Mature and immature platelets during the first week after birth and incidence of patent ductus arteriosus

Mature and immature platelets during the first week after birth and incidence of patent ductus arteriosus

Thrombocytopenia is a risk factor for patent ductus arteriosus. Immature and mature platelets exhibit distinct haemostatic properties; however, whether platelet maturity plays a role in postnatal, ductus arteriosus closure is unknown. In this observational study, counts of immature and mature platel...

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Veröffentlicht in:Cardiology in the young 2020-06, Vol.30 (6), p.769-773
Hauptverfasser: Sallmon, Hannes, Metze, Boris, Koehne, Petra, Opgen-Rhein, Bernd, Weiss, Katja, Will, Joachim C, Franke, Christina Victoria, Hansmann, Georg, Koestenberger, Martin, Bührer, Christoph, Berger, Felix, Weber, Sven C, Cremer, Malte
Format: Artikel
Sprache:eng
Schlagworte:
Birth weight
Blood platelets
Blood Platelets - pathology
Congenital diseases
Coronary vessels
Doppler effect
Ductus Arteriosus, Patent - blood
Ductus Arteriosus, Patent - diagnosis
Ductus Arteriosus, Patent - physiopathology
Echocardiography
Female
Gestational Age
Hemodynamics
Humans
Incidence
Infant, Newborn
Infant, Premature, Diseases - blood
Infant, Premature, Diseases - diagnosis
Infant, Premature, Diseases - physiopathology
Infant, Very Low Birth Weight - blood
Infants
Logistic Models
Low birth weight
Male
Newborn babies
Platelet Count
Platelets
Premature babies
Regression analysis
Risk analysis
Risk factors
ROC Curve
Thrombocytopenia
Weight
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Zusammenfassung:Thrombocytopenia is a risk factor for patent ductus arteriosus. Immature and mature platelets exhibit distinct haemostatic properties; however, whether platelet maturity plays a role in postnatal, ductus arteriosus closure is unknown. In this observational study, counts of immature and mature platelets (=total platelet count - immature platelet count) were assessed on days 1, 3, and 7 of life in very low birth weight infants (
ISSN:1047-9511
1467-1107
DOI:10.1017/S1047951120000943