Total synthesis of Myc-IV(C16:0, S) via automated electrochemical assembly

Total synthesis of Myc-IV(C16:0, S) via automated electrochemical assembly

Total synthesis of Myc-IV(C16:0, S) via automated electrochemical assembly has been accomplished. This tetrasaccharide has been studied as a symbiotic signal molecule of Arbuscular Mycorrhiza fungi. We have achieved stereoselective synthesis of a disaccharide building block using the mixed-electroly...

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Veröffentlicht in:Carbohydrate research 2020-06, Vol.492, p.108018-108018, Article 108018
Hauptverfasser: Yano, Kumpei, Itoh, Toshiyuki, Nokami, Toshiki
Format: Artikel
Sprache:eng
Schlagworte:
Automation
Carbohydrate Conformation
Electrochemical Techniques
Mycorrhizae - chemistry
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Zusammenfassung:Total synthesis of Myc-IV(C16:0, S) via automated electrochemical assembly has been accomplished. This tetrasaccharide has been studied as a symbiotic signal molecule of Arbuscular Mycorrhiza fungi. We have achieved stereoselective synthesis of a disaccharide building block using the mixed-electrolyte system for electrochemical glycosylation; 2 + 1+1 strategy enables us to access the tetrasaccharide precursor and complete the synthesis Myc-IV(C16:0, S) efficiently. [Display omitted]
ISSN:0008-6215
1873-426X
DOI:10.1016/j.carres.2020.108018