S‐(4‐nitrobenzyl)‐6‐thioinosine: Tritium labelling at high specific activity

The one‐step tritiation of S‐(4‐nitrobenzyl)‐6‐thioinosine is described with characterization of the product by tritium NMR as well as mass spectrometry. The storage, stability, and repurification of [benzyl methylene‐3H]S‐(4‐nitrobenzyl)‐6‐thioinosine are also discussed. The one step tritiation of...

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Veröffentlicht in:	Journal of labelled compounds & radiopharmaceuticals 2020-07, Vol.63 (9), p.426-429
Hauptverfasser:	Filer, Crist N., Byon, Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	Isotope Labeling Labeling Mass spectrometry Mass spectroscopy NMR Nuclear magnetic resonance nucleoside transporters Shelf life S‐(4‐nitrobenzyl)‐6‐thioinosine Thioinosine - analogs & derivatives Thioinosine - chemistry Tritiation Tritium Tritium - chemistry tritium NMR
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Zusammenfassung:	The one‐step tritiation of S‐(4‐nitrobenzyl)‐6‐thioinosine is described with characterization of the product by tritium NMR as well as mass spectrometry. The storage, stability, and repurification of [benzyl methylene‐3H]S‐(4‐nitrobenzyl)‐6‐thioinosine are also discussed. The one step tritiation of S‐(4‐nitrobenzyl)‐6‐thioinosine is described with characterization of the product by tritium NMR as well as mass spectrometry. The storage, stability and repurification of [benzyl methylene‐3H]S‐(4‐nitrobenzyl)‐6‐thioinosine are also discussed.
ISSN:	0362-4803 1099-1344 1099-1344
DOI:	10.1002/jlcr.3844