Profile of Immunoglobulin G and IgM Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Profile of Immunoglobulin G and IgM Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Abstract We profiled the serological responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein and spike (S) glycoprotein. The majority of the patients developed robust antibody responses between 17 and 23 days after illness onset. Delayed, but stronger, anti...

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Veröffentlicht in:Clinical infectious diseases 2020-11, Vol.71 (16), p.2255-2258
Hauptverfasser: Qu, Jiuxin, Wu, Chi, Li, Xiaoyong, Zhang, Guobin, Jiang, Zhaofang, Li, Xiaohe, Zhu, Qing, Liu, Lei
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Antibodies, Viral - blood
China
COVID-19 - diagnosis
COVID-19 - immunology
COVID-19 Testing
Female
Hospitalization
Humans
Immunity, Humoral
Immunoglobulin G - blood
Immunoglobulin M - blood
Male
Middle Aged
SARS-CoV-2
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Zusammenfassung:Abstract We profiled the serological responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein and spike (S) glycoprotein. The majority of the patients developed robust antibody responses between 17 and 23 days after illness onset. Delayed, but stronger, antibody responses were observed in critical patients.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciaa489