Predicting the risk of sarcopenia in elderly patients with patellar fracture: development and assessment of a new predictive nomogram

Purpose. To develop a risk prediction model for postoperative sarcopenia in elderly patients with patellar fractures in China. Patients and methods. We conducted a community survey of patients aged >= 55 years who underwent surgery for patellar fractures between January 2013 and October 2018, thr...

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Veröffentlicht in:PeerJ (San Francisco, CA) CA), 2020-04, Vol.8, p.e8793-e8793, Article 8793
Hauptverfasser: Chen, Yi-sheng, Cai, Yan-xian, Kang, Xue-ran, Zhou, Zi-hui, Qi, Xin, Ying, Chen-ting, Zhang, Yun-peng, Tao, Jie
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Sprache:eng
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Zusammenfassung:Purpose. To develop a risk prediction model for postoperative sarcopenia in elderly patients with patellar fractures in China. Patients and methods. We conducted a community survey of patients aged >= 55 years who underwent surgery for patellar fractures between January 2013 and October 2018, through telephone interviews, community visits, and outpatient follow-up. We established a predictive model for assessing the risk of sarcopenia after patellar fractures. We developed the prediction model by combining multivariate logistic regression analysis with the least absolute shrinkage model and selection operator regression (lasso analysis) as well as the Support Vector Machine (SVM) algorithm. The predictive quality and clinical utility of the predictive model were determined using C-index, calibration plots, and decision curve analysis. We also conducted internal sampling methods for qualitative assessment. Result. We recruited 137 participants (53 male; mean age, 65.7 years). Various risk factors were assessed, and low body mass index and advanced age were identified as the most important risk factor (P
ISSN:2167-8359
2167-8359
DOI:10.7717/peerj.8793