Per-Vessel Level Analysis of Fractional Flow Reserve and Instantaneous Wave-Free Ratio Discordance　― Insights From the AJIP Registry

Per-Vessel Level Analysis of Fractional Flow Reserve and Instantaneous Wave-Free Ratio Discordance　― Insights From the AJIP Registry

Background:The per-vessel level impact of physiological pattern of disease on the discordance between fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) has not been clarified.Methods and Results:Using the AJIP registry, vessels with FFR/iFR discordance (133/671 [19.8%]) were anal...

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Veröffentlicht in:Circulation Journal 2020/05/25, Vol.84(6), pp.1034-1038
Hauptverfasser: Warisawa, Takayuki, Cook, Christopher M., Seligman, Henry, Howard, James P., Ahmad, Yousif, Rajkumar, Christopher, Doi, Shunichi, Nakayama, Masafumi, Tanigaki, Toru, Omori, Hiroyuki, Nakajima, Akihiro, Yamanaka, Futoshi, Goto, Sonoka, Yakuta, Yohei, Karube, Kenichi, Uetani, Teruyoshi, Kikuta, Yuetsu, Shiono, Yasutsugu, Kawase, Yoshiaki, Nishina, Hidetaka, Nakamura, Sunao, Escaned, Javier, Akashi, Yoshihiro J., Matsuo, Hitoshi, Davies, Justin E.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Cardiac Catheterization
Coronary Artery Disease - diagnosis
Coronary Artery Disease - physiopathology
Coronary Vessels - physiopathology
Diffuse disease
Female
Fractional flow reserve
Fractional Flow Reserve, Myocardial
Humans
Instantaneous wave-free ratio
Male
Middle Aged
Predictive Value of Tests
Registries
Severity of Illness Index
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Zusammenfassung:Background:The per-vessel level impact of physiological pattern of disease on the discordance between fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) has not been clarified.Methods and Results:Using the AJIP registry, vessels with FFR/iFR discordance (133/671 [19.8%]) were analyzed. In the left anterior descending artery (LAD), physiologically diffuse disease, as assessed by pressure-wire pullback, was associated with FFR−/iFR+ (83.3% [40/48]), while physiologically focal disease was associated with FFR+/iFR− (57.4% [31/54]), significantly (P
ISSN:1346-9843
1347-4820
1347-4820
DOI:10.1253/circj.CJ-19-0785