Improved overall survival is still observed in patients receiving delayed adjuvant chemotherapy after pancreaticoduodenectomy for pancreatic adenocarcinoma

Improved overall survival is still observed in patients receiving delayed adjuvant chemotherapy after pancreaticoduodenectomy for pancreatic adenocarcinoma

Adjuvant chemotherapy (AC) is associated with improved survival following resection of pancreatic adenocarcinoma but is frequently delayed or deferred due to perioperative complications or patient deconditioning. The aim of this study was to assess impact of delayed AC on overall survival after panc...

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Veröffentlicht in:HPB (Oxford, England) England), 2020-11, Vol.22 (11), p.1542-1548
Hauptverfasser: Turner, Megan C., Masoud, Sabran J., Cerullo, Marcelo, Adam, Mohamed A., Shah, Kevin N., Blazer, Dan G., Abbruzzese, James L., Zani, Sabino
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Sprache:eng
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Zusammenfassung:Adjuvant chemotherapy (AC) is associated with improved survival following resection of pancreatic adenocarcinoma but is frequently delayed or deferred due to perioperative complications or patient deconditioning. The aim of this study was to assess impact of delayed AC on overall survival after pancreaticoduodenectomy for pancreatic head adenocarcinoma. Patients with stage I-III pancreatic head adenocarcinoma in the 2006–2015 National Cancer Database were grouped by timing of AC (
ISSN:1365-182X
1477-2574
DOI:10.1016/j.hpb.2020.03.006