Serum total carbon dioxide as a prognostic factor for 28-day mortality in patients with sepsis

Serum total carbon dioxide as a prognostic factor for 28-day mortality in patients with sepsis

Metabolic acidosis is commonly associated with the disease severity in patients with sepsis or septic shock. This study was performed to investigate the association between serum total carbon dioxide (TCO2) concentration and 28-day mortality in patients with sepsis. This study was a multicenter retr...

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Veröffentlicht in:The American journal of emergency medicine 2021-06, Vol.44, p.277-283
Hauptverfasser: Kim, Jin Hee, Jang, Dong-Hyun, Jo, You Hwan, Suh, Gil Joon, Kwon, Woon Yong, Lee, Jae Hyuk, Shin, Jonghwan, Park, Inwon, Lee, Che Uk, Lee, Sang-Min
Format: Artikel
Sprache:eng
Schlagworte:
Acidosis
Bicarbonates
Body mass index
Carbon dioxide
Creatinine
Data collection
Emergency medical care
Hypotension
Infections
Laboratories
Lactic acid
Medical prognosis
Metabolic acidosis
Metabolism
Mortality
Patients
pH effects
Prognosis
Regression analysis
Sepsis
Septic shock
Teaching hospitals
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Zusammenfassung:Metabolic acidosis is commonly associated with the disease severity in patients with sepsis or septic shock. This study was performed to investigate the association between serum total carbon dioxide (TCO2) concentration and 28-day mortality in patients with sepsis. This study was a multicenter retrospective cohort study of patients with sepsis or septic shock. The relationships between serum TCO2 and 28-day mortality, bicarbonate, pH, lactate, and anion gap were determined with cubic spline curves. The patients were divided into four groups according to their serum TCO2 concentration: Group I (TCO2 > 20 mmol/l), Group II (15 
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2020.04.006