Efficacy of Intragastric Balloons for Weight Loss in Overweight and Obese Adults: a Systematic Review and Meta-analysis of Randomized Controlled Trials

Intragastric balloons (IGB) are the most widely used endoscopic bariatric and metabolic therapies. We aimed to evaluate the efficacy of IGB in comparison with sham or lifestyle interventions for weight loss in overweight and obese patients. This systematic review and meta-analysis was performed foll...

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Veröffentlicht in:Obesity surgery 2020-07, Vol.30 (7), p.2743-2753
Hauptverfasser: Kotinda, Ana Paula Samy Tanaka, de Moura, Diogo Turiani Hourneaux, Ribeiro, Igor Braga, Singh, Shailendra, da Ponte Neto, Alberto Machado, Proença, Igor Mendonça, Flor, Marcelo Mochate, de Souza, Karina Lopes, Bernardo, Wanderley Marques, de Moura, Eduardo Guimarães Hourneaux
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container_end_page 2753
container_issue 7
container_start_page 2743
container_title Obesity surgery
container_volume 30
creator Kotinda, Ana Paula Samy Tanaka
de Moura, Diogo Turiani Hourneaux
Ribeiro, Igor Braga
Singh, Shailendra
da Ponte Neto, Alberto Machado
Proença, Igor Mendonça
Flor, Marcelo Mochate
de Souza, Karina Lopes
Bernardo, Wanderley Marques
de Moura, Eduardo Guimarães Hourneaux
description Intragastric balloons (IGB) are the most widely used endoscopic bariatric and metabolic therapies. We aimed to evaluate the efficacy of IGB in comparison with sham or lifestyle interventions for weight loss in overweight and obese patients. This systematic review and meta-analysis was performed following the PRISMA guidelines. Electronic searches were performed to identify randomized controlled trials, which compared IGB with sham or lifestyle intervention. Thirteen RCTs with 1523 patients were included. The difference in mean %EWL and %TWL at follow-up was 17.98%, and 4.40%, respectively, which was significantly higher in the IGB group. Similarly, the difference in mean AWL and BMIL was 6.12 kg, and 2.13 kg/m 2 , respectively. IGB therapy is more effective than lifestyle intervention alone for weight loss in overweight and obese adults.
doi_str_mv 10.1007/s11695-020-04558-5
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subjects Adult
Clinical trials
Gastric Balloon
Humans
Lifestyles
Medicine
Medicine & Public Health
Meta-analysis
Obesity
Obesity - therapy
Obesity, Morbid - surgery
Randomized Controlled Trials as Topic
Review
Surgery
Systematic review
Treatment Outcome
Weight Loss
title Efficacy of Intragastric Balloons for Weight Loss in Overweight and Obese Adults: a Systematic Review and Meta-analysis of Randomized Controlled Trials
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