Visible-light-controllable drug release from multilayer-coated microneedles

A method for the generation of visible-light-controllable drug release polyelectrolyte multilayers on poly(l-lactide) (PLLA) microneedles is developed by host-guest chemistry. In response to visible light irradiation, model drugs encapsulated on polyelectrolyte multilayers transfer into the skin fol...

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Veröffentlicht in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2017-09, Vol.5 (34), p.7014-7017
Hauptverfasser: Zheng, Zhiqiang, Ye, Haixia, Wang, Juan, Zhang, Taoye, You, Qingliang, Li, Haohuan, He, Rongxiang, Chen, Yong, Zhang, Weiying, Cao, Yiping
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Sprache:eng
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Zusammenfassung:A method for the generation of visible-light-controllable drug release polyelectrolyte multilayers on poly(l-lactide) (PLLA) microneedles is developed by host-guest chemistry. In response to visible light irradiation, model drugs encapsulated on polyelectrolyte multilayers transfer into the skin following brief microneedle application.
ISSN:2050-750X
2050-7518
DOI:10.1039/c7tb01546a