Fatal Strongyloides hyperinfection syndrome in renal transplant recipients: a neglected cause of immunosuppression‐related mortality

Patient 1 was a 59-year-old male originally from Vietnam with end-stage renal disease secondary to IgA nephropathy, with hypertension and T2DM. He underwent cadaveric renal transplantation with basiliximab and methylprednisolone induction followed by maintenance tacrolimus, mycophenolate mofetil and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Histopathology 2020-07, Vol.77 (1), p.156-159
Hauptverfasser: Sekhawat, Vivek, Hawkins‐Van Der Cingel, Gerlineke, Karia, Yash, Clarke, Lindsey, Rajakariar, Ravindra, Sammartino, Cinzia
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Patient 1 was a 59-year-old male originally from Vietnam with end-stage renal disease secondary to IgA nephropathy, with hypertension and T2DM. He underwent cadaveric renal transplantation with basiliximab and methylprednisolone induction followed by maintenance tacrolimus, mycophenolate mofetil and tapering prednisolone. He was treated for CMV reactivation and developed an acneiform folliculitis during the post-transplant course which was otherwise uncomplicated. He presented three months later with abdominal pain, constipation and vomiting. On day 3 of admission he deteriorated rapidly, becoming clinically septic.
ISSN:0309-0167
1365-2559
DOI:10.1111/his.14111